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Consultant-Led • Reversal-First • The Shard, London

Can osteoporosis be reversed? Yes. The window before symptoms is the window that matters.

We don’t just slow bone loss — we rebuild it. Four levers, one consultant-led pathway: nutrition, strength training, precisely targeted medication, and the mindset to sustain change. Measured on DXA, year on year.

Book a Consultant AssessmentTake the Bone Confidence Score™
8–12% / year
Documented BMD improvementTypical bone density gain achieved within the BoneRevive® programme — measurable on DXA, year on year.
524,000 / year
UK fragility fracturesWith around 1,150 deaths each month linked to osteoporotic fracture. Most are preventable with earlier identification.
2 US patents
In osteoporosis reversal & preventionHeld by Dr Taher Mahmud FRCP, Consultant Rheumatologist and Co-Founder of LOC.
Where to begin

Three routes into LOC

Whether for personal assessment, clinical referral, or organisational risk — there is a defined entry point.

For Individuals

Personal bone health assessment

Consultant-led DXA interpretation, fracture risk quantification, secondary-cause screening, and a personalised pathway. For anyone with risk factors, post-menopausal change, or concern.

Book an assessment →
For Clinicians

Refer a patient

Specialist referrals welcomed for complex cases, treatment failure, atypical presentations, secondary osteoporosis, and patients seeking anabolic-first management. Reports issued to referring clinician.

Refer a patient →
For Organisations

KPHRI™ — Key Person Health Review

A B2B health intelligence instrument for boards, partnerships, and key persons. Treats clinical risk as a category of organisational risk. Distributed via insurers, banks, and professional firms.

Explore KPHRI™ →
The LOC clinical position

Reversal-first. Measured forward. Not merely the slowing of loss, but the rebuilding of bone.

Most osteoporosis care in the United Kingdom is anti-resorptive — it slows the rate at which bone is lost. That is necessary, and often appropriate. It is rarely sufficient.

LOC’s clinical philosophy goes further. Where the clinical picture allows, the objective is to actively rebuild bone — to increase bone mineral density forward, year on year, measurable on DXA. The BoneRevive® programme typically achieves 8–12% BMD improvement per year. Over a five-year horizon, that is a fundamentally different fracture trajectory.

This requires a complete clinical picture: density, microarchitecture, turnover markers, nutritional status, hormonal context, medication review, and personal risk profile. It requires structured monitoring, not single-visit care. And it requires consultant-level judgement about when to use medication, which agent, for what duration — and when not to.

The window in which intervention is most effective is precisely the window in which the disease is silent. Identifying that window — before the first fracture — is the work.
The Bone Pathway™

A four-stage clinical pathway, structured around measurable outcomes

Each stage produces a deliverable — a quantified risk picture, a personalised plan, a measurable change. Patients are not handed a prescription and discharged; they are placed within a pathway that is monitored over time.

STAGE 01

Consultant assessment

Detailed clinical history, physical examination, and consultation with Dr Mahmud or a senior member of the team. Identification of risk factors, secondary causes, and reversible contributors. Output: a structured clinical formulation.

STAGE 02

Diagnostic measurement

DXA scan, vertebral fracture assessment, trabecular bone score where indicated, bone turnover markers, and a focused metabolic panel. FRAX or QFracture risk synthesis. Output: a quantified picture of bone status and 10-year fracture risk.

STAGE 03

Personalised pathway

A bespoke plan combining nutrition, loading exercise, lifestyle modification, secondary-cause management, and — where appropriate — anabolic or anti-resorptive pharmacological treatment. Output: an active programme with defined milestones.

STAGE 04

Monitoring and optimisation

Repeat DXA, ongoing turnover marker review, treatment adjustment, and longitudinal capability tracking. Bone health is not a single intervention; it is a sustained programme. Output: measurable forward change, year on year.

Clinical Leadership

Dr Taher Mahmud FRCP

Consultant Rheumatologist
Co-Founder, London Osteoporosis Clinic
Trustee, Global Osteoporosis Foundation
FRCP (Royal College of Physicians)
Two US patents in osteoporosis reversal & prevention
25+ years in metabolic bone disease and rheumatology
NHS Consultant 2000-2026 across multiple Trusts
Founder, BoneRevive® and the Bone Pathway™

Dr Taher Mahmud is a Consultant Rheumatologist who has built his career around a single clinical conviction: that osteoporosis is not an inevitable consequence of ageing, but a measurable, modifiable, and frequently reversible condition.

His clinical work, his patents, and the LOC programme are built on this position. The methods are not speculative — they are anchored in measurable bone density gain and longitudinal outcomes data, delivered through a structured pathway and monitored on DXA over time.

As a Trustee of the Global Osteoporosis Foundation, he leads the Fracture-Free Future 2040™ initiative — a long-term effort to eliminate preventable fragility fractures globally.

Where LOC is delivered, recognised, and trusted
HCA Healthcare UK
Nuffield Health
BUPA
Vitality
AXA Health
Simplyhealth
NHS
GE Healthcare
Siemens Healthineers
Philips
Hologic
Toshiba Medical
Bone Health Insights

Latest from the clinic

Clinical · March 2026

Why osteoporosis treatment is a strategy, not a prescription

Medication alone is rarely sufficient to rebuild bone. The foundations of strong bone are built through nutrition, loading, and a structured clinical plan — with drugs deployed precisely.

Clinical · March 2026

What lives inside your bones

Bones are not dry, static structures. They are metabolically active organs, housing marrow and stem cells. Understanding what lives inside the bone clarifies how nutrition and hormones drive bone strength.

All insights

Read the full library

Clinical analysis, evidence reviews, and structured commentary on bone health, fracture prevention, and the wider context of long-term capability.

Where We See Patients

Clinical locations

London

HCA at The Shard

32 St Thomas Street
London SE1 9BS
+44 (0)20 7193 7867
Kent

Nuffield Tunbridge Wells Hospital

Consultations and follow-up
by appointment
+44 (0)20 7193 7867

The earlier the assessment, the more the pathway can do.

A consultant-led bone health assessment quantifies your position, identifies modifiable factors, and defines the pathway forward — with measurable outcomes tracked year on year.

Book a Consultant AssessmentTake the Bone Confidence Score™
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